When a Spanish Jesuit goes into the South American wilderness to build a mission in the hope of converting the Indians of the region, a slave hunter is converted and joins his mission. When Spain sells the colony to Portugal, they are forced to defend all they have built against the Portuguese aggressors.
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| Directing | Roland Joffé | Director |
| Production | Fernando Ghia | Producer |
| Production | David Puttnam | Producer |
| Production | Alejandro Azzano | Executive Producer |
| Production | Felipe López Caballero | Executive Producer |
| Camera | Chris Menges | Director of Photography |
| Editing | Jim Clark | Editor |
| Writing | Robert Bolt | Screenplay |
| Production | Susie Figgis | Casting |
| Production | Juliet Taylor | Casting |
| Costume & Make-Up | Enrico Sabbatini | Costume Design |
| Sound | Ennio Morricone | Original Music Composer |
| Art | Stuart Craig | Production Design |
| Art | Norman Dorme | Supervising Art Director |
| Art | George Richardson | Art Direction |
| Crew | Vic Armstrong | Stunt Coordinator |
| Art | Paul Bradburn | Props |
| Sound | Ric O'Connor | Sound Editor |
| Writing | Robert Bolt | Original Story |
| Costume & Make-Up | Charlotte Bakker | Wig Designer |
| Costume & Make-Up | Elaine Bowerbank | Hairstylist |
| Costume & Make-Up | Sallie Evans | Makeup Artist |
| Costume & Make-Up | Magdalen Gaffney | Makeup Artist |
| Costume & Make-Up | Paula Gillespie | Key Hair Stylist |
| Costume & Make-Up | Geraldine Jones | Hairstylist |
| Costume & Make-Up | Stephanie Kaye | Hairstylist |
| Costume & Make-Up | Ken Lintott | Makeup Artist |
| Costume & Make-Up | Tommie Manderson | Makeup Supervisor |
| Costume & Make-Up | Wendy Rawson | Hairstylist |
| Directing | Salvatore Basile | Assistant Director |
| Directing | Salvatore Basile | Assistant Director |
| Directing | Uberto Pasolini | Third Assistant Director |
| Directing | Gerry Toomey | Second Assistant Director |
| Directing | Bill Westley | First Assistant Director |
| Directing | Kevin Westley | Additional Second Assistant Director |
| Sound | Christopher Ackland | Sound Editor |
| Sound | Martin Evans | Dialogue Editor |
| Sound | Ian Fuller | ADR Editor |
| Sound | Bill Rowe | ADR Mixer |
| Sound | Clive Winter | Sound Mixer |
| Sound | Lionel Strutt | ADR Mixer |
| Crew | Steve Crawley | Special Effects |
| Crew | Peter Fern | Special Effects Technician |
| Crew | Martin Gant | Special Effects Technician |
| Visual Effects | Peter Hutchinson | Special Effects Supervisor |
| Crew | Peter Skehan | Special Effects Technician |
| Crew | Andrew Smith | Special Effects Technician |
| Crew | Marco Yepes | Special Effects Assistant |
| Visual Effects | Costas Charitou | Visual Effects |
| Crew | Jordi Casares | Stunts |
| Crew | Billy Horrigan | Stunts |
| Crew | Niamh McAnally | Stunts |
| Crew | Bronco McLoughlin | Stunts |
| Crew | Miguel Pedregosa | Stunts |
| Crew | Tito Tomassini | Stunts |
| Camera | Felipe Aljure | Assistant Camera |
| Camera | Jan Pester | Second Unit Director of Photography |
| Camera | Robin Vidgeon | Second Unit Director of Photography |
| Art | Richard Morrison | Title Designer |
| Crew | Héctor Babenco | Thanks |
| Editing | Bryan Oates | First Assistant Editor |
| Camera | David Appleby | Still Photographer |
