Villainous Gru lives up to his reputation as a despicable, deplorable and downright unlikable guy when he hatches a plan to steal the moon from the sky. But he has a tough time staying on task after three orphans land in his care.
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| Directing | Pierre Coffin | Director |
| Directing | Chris Renaud | Director |
| Writing | Ken Daurio | Screenplay |
| Writing | Sergio Pablos | Story |
| Writing | Cinco Paul | Screenplay |
| Editing | Gregory Perler | Editor |
| Production | Sergio Pablos | Executive Producer |
| Production | Chris Meledandri | Producer |
| Production | Janet Healy | Producer |
| Production | John Cohen | Producer |
| Sound | Heitor Pereira | Original Music Composer |
| Production | Nina Rappaport | Executive Producer |
| Art | Yarrow Cheney | Production Design |
| Art | Eric Guillon | Art Direction |
| Writing | Stephan Franck | Storyboard |
| Writing | Cal Brunker | Storyboard |
| Crew | Jeannine Berger | Post Production Supervisor |
| Visual Effects | Mitja Rabar | Animation |
| Visual Effects | Yannick Honore | Animation |
| Sound | Pharrell Williams | Original Music Composer |
| Production | Mary Hidalgo | Casting |
| Sound | Armen Ksajikian | Musician |
| Visual Effects | Fabrice Joubert | Animation |
| Sound | Kevin Kaska | Orchestrator |
| Editing | Pam Ziegenhagen | Editor |
| Production | Robert Taylor | Associate Producer |
| Editing | Claire Dodgson | Additional Editing |
| Editing | Steven Liu | Additional Editing |
| Sound | Franklin Jones III | ADR Editor |
| Sound | Daniel Laurie | ADR Supervisor |
| Production | Holly Dorff | ADR Voice Casting |
| Visual Effects | Lionel Gallat | Animation Director |
| Visual Effects | Anais Perlot | Animation Manager |
| Visual Effects | Laurent de la Chapelle | Animation Supervisor |
| Visual Effects | Daniel Callaby | Animation |
| Visual Effects | Lang-Willar Chloe | Animation |
| Visual Effects | Céline Chotard | Animation |
| Visual Effects | Mathilde Fabry | Animation |
| Visual Effects | Audrey Fobis | Animation |
| Visual Effects | Vincent Garcia | Animation |
| Visual Effects | Guillaume Herent | Animation |
| Visual Effects | Silke Jager | Animation |
| Visual Effects | Francois F. Laurent | Animation |
| Visual Effects | Renaud Mégange | Animation |
| Visual Effects | Elena Ortego | Animation |
| Visual Effects | Julen Santiago | Animation |
| Visual Effects | Loïc Miermont | Animation |
| Visual Effects | Mathieu Gérard | Animation |
| Visual Effects | Moïse Essame | Animation |
| Visual Effects | Jean-François Macé | Visual Effects Technical Director |
| Visual Effects | Jean-François Barthélémy | Animation |
| Visual Effects | Clementine Tronel | Animation |
| Visual Effects | Karin Kempf | Animation |
| Art | Katie Ballentine | Art Department Coordinator |
| Editing | Gilad Carmel | Assistant Editor |
| Editing | Karen Hathaway | Assistant Editor |
| Editing | Michael Rostker | Assistant Editor |
| Production | Solenn Colas | Assistant Production Manager |
| Production | Karine Friang | Assistant Production Manager |
| Production | Joy Poirel | Assistant Production Manager |
| Crew | Leff Lefferts | Sound Design Assistant |
| Editing | Patrick Voetberg | Associate Editor |
| Production | Mary Hidalgo | Casting Consultant |
| Crew | Bruno Chauffard | CG Supervisor |
| Visual Effects | Carter Goodrich | Character Designer |
| Visual Effects | Eric Guillon | Character Designer |
| Crew | Tony Gonzalez | Choreographer |
| Visual Effects | Sergio Casas | Color Designer |
| Visual Effects | Olivier Delabarre | Color Designer |
| Visual Effects | Clément Griselain | Color Designer |
| Visual Effects | Carlos Felipe León Ortiz | Color Designer |
| Editing | Terry Claborn | Color Timer |
| Sound | Chris Westlake | Original Music Composer |
| Sound | Tim Davies | Conductor |
| Sound | Joey Newman | Conductor |
| Visual Effects | Jerome Auliac | Digital Compositors |
| Visual Effects | Florian Bestel | Digital Compositors |
| Visual Effects | Matthieu Chatelier | Digital Compositors |
| Visual Effects | Jean-Nicolas Costa | Digital Compositors |
| Visual Effects | Rudyard Cretenet | Digital Compositors |
| Visual Effects | Clement Darbois | Digital Compositors |
| Visual Effects | Antoine Douadi | Digital Compositors |
| Visual Effects | Christophe Duflaut | Digital Compositors |
| Visual Effects | Lucien Fostier | Digital Compositors |
| Visual Effects | Delphine Garrelis | Digital Compositors |
| Visual Effects | Philippe Huberdeau | Digital Compositors |
| Visual Effects | Jola Kudela | Digital Compositors |
| Visual Effects | Khaled Labidi | Digital Compositors |
| Visual Effects | François Le Bastard | Digital Compositors |
| Visual Effects | Thomas Lefebvre | Digital Compositors |
| Visual Effects | Jeanne Loyer | Digital Compositors |
| Visual Effects | Olivier Lukaszczyk | Digital Compositors |
| Visual Effects | Gaston Marcotti | Digital Compositors |
| Visual Effects | Maya Pelle | Digital Compositors |
| Visual Effects | Alexis Peraste | Digital Compositors |
| Visual Effects | Simon Rafin | Digital Compositors |
| Visual Effects | Dane Rapaport | Digital Compositors |
| Visual Effects | Marine Samyn | Digital Compositors |
| Visual Effects | Niranjan Siva | Digital Compositors |
| Visual Effects | Jeremy Séguin | Digital Compositors |
| Visual Effects | Gerome Viavant | Digital Compositors |
| Visual Effects | Anthony Voisin | Digital Compositors |
| Visual Effects | Stephan Guerin | Digital Compositors |
| Visual Effects | Stephanie Saillard | Digital Compositors |
| Editing | Jason Hanel | Digital Intermediate |
| Editing | Tyler Werrin | Editorial Production Assistant |
| Editing | Josh Morgan | Editorial Coordinator |
| Editing | Alex Dowding | Editorial Manager |
| Editing | Ed Fuller | First Assistant Editor |
| Sound | Sean England | Foley |
| Sound | E. Larry Oatfield | Foley Editor |
| Visual Effects | Michael Crouzat | Key Animation |
| Visual Effects | Patrick Delage | Lead Animator |
| Visual Effects | Jean Hemez | Lead Animator |
| Visual Effects | Stephane Mangin | Lead Animator |
| Crew | Bart Boirot | Supervising Animator |
| Lighting | Justine Codron | Lighting Artist |
| Lighting | Alexandre Bermond | Lighting Artist |
| Lighting | Saïdou Bernabé | Lighting Artist |
| Lighting | Vincent Blanqué | Lighting Artist |
| Lighting | Cédric Burkarth | Lighting Artist |
| Lighting | Blandine Chanteur | Lighting Artist |
| Lighting | Pierre Gobilliard | Lighting Artist |
| Lighting | Pierre Lopes | Lighting Artist |
| Lighting | Olivier Martiny | Lighting Artist |
| Lighting | Mathieu Le Meur | Lighting Artist |
| Lighting | Matthieu Molina | Lighting Artist |
| Lighting | Gourdal Sebastien | Lighting Artist |
| Lighting | Hugues Ssosse | Lighting Artist |
| Lighting | Ephraïm Drouet | Lighting Artist |
| Lighting | Benoit Fournol | Lighting Artist |
| Lighting | Vivian David | Lighting Artist |
| Sound | Gavin Greenaway | Music Director |
| Sound | Slamm Andrews | Music Editor |
| Sound | Kathy Nelson | Music Supervisor |
| Sound | Scott Hosfeld | Musician |
| Sound | Satnam Ramgotra | Musician |
| Sound | Bruce Fowler | Orchestrator |
| Sound | Walt Fowler | Orchestrator |
| Sound | Rick Giovinazzo | Orchestrator |
| Sound | Carl Rydlund | Orchestrator |
| Sound | Peter Buccellato | ADR & Dubbing |
| Sound | Roy Latham | ADR & Dubbing |
| Sound | Carlos Sotolongo | ADR & Dubbing |
| Crew | Miguel Ángel Poveda | Post Production Supervisor |
| Production | Julien Sabourdin | Production Accountant |
| Production | Frédéric Greene | Production Accountant |
| Production | Ségolène Amice Lagny | Production Coordinator |
| Directing | Dave Rosenbaum | Script Supervisor |
| Production | Dave Rosenbaum | Executive In Charge Of Production |
| Production | Christelle Balcon | Production Manager |
| Production | Christina DeSilva | Production Manager |
| Production | Jean-Luc Florinda | Production Manager |
| Production | Wassila Lmouaci | Production Manager |
| Production | Jill Ragaway | Production Manager |
| Sound | Tom Johnson | Sound Re-Recording Mixer |
| Sound | Chris Scarabosio | Sound Re-Recording Mixer |
| Sound | Chris Scarabosio | Sound Designer |
| Sound | Chris Scarabosio | Supervising Sound Editor |
| Lighting | Guillaume Boudeville | Rigging Supervisor |
| Crew | Fabian Marascuillo | Score Engineer |
| Sound | Hans Zimmer | Music Score Producer |
| Sound | Oren Hadar | Scoring Mixer |
| Directing | Mary Bills | Script Supervisor |
| Art | Paul Mager | Set Designer |
| Art | Vincent Massy | Set Designer |
| Crew | Eric Placoly | Software Engineer |
| Sound | Steve Bissinger | Sound Effects Editor |
| Sound | David C. Hughes | Sound Effects Editor |
| Sound | Jeremy Bowker | Sound Effects Editor |
| Sound | Michael Jesmer | Sound Recordist |
| Sound | Sandy Buchanan | Sound Recordist |
| Art | Loïc Rastout | Set Designer |
| Crew | Christophe Asselin | Thanks |
| Crew | Rodolphe Chabrier | Thanks |
| Crew | Christine Lagarde | Thanks |
| Camera | Nicole Rivelli | Still Photographer |
| Crew | Pierre Avon | Supervising Animator |
| Crew | Nicolas Bauduin | Supervising Animator |
| Crew | Pierre Leduc | Supervising Animator |
| Crew | Elisabeth Patte | Supervising Animator |
| Crew | Julien Soret | Supervising Animator |
| Sound | Vicki Hiatt | Supervising Music Editor |
| Sound | Dennis Leonard | Supervising Sound Editor |
| Visual Effects | Robin Joseph | Visual Development |
| Visual Effects | Charles Chorein | Visual Effects |
| Visual Effects | Vincent Houze | Visual Effects |
| Visual Effects | Elodie Labbe | VFX Artist |
| Visual Effects | Mathieu Malard | VFX Artist |
| Visual Effects | Emmanuelle Carlier | Visual Effects Producer |
| Visual Effects | Marie-Claire Bazart | VFX Supervisor |
| Visual Effects | Bart Boirot | Lead Animator |
| Sound | Pharrell Williams | Songs |
