Test pilot Tuck Pendleton volunteers to test a special vessel for a miniaturization experiment. Accidentally injected into a neurotic hypochondriac, Jack Putter, Tuck must convince Jack to find his ex-girlfriend, Lydia Maxwell, to help him extract Tuck and his ship and re-enlarge them before his oxygen runs out.
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| Sound | Jerry Goldsmith | Original Music Composer |
| Writing | Jeffrey Boam | Screenplay |
| Writing | Chip Proser | Screenplay |
| Crew | Pete Kozachik | Special Effects |
| Directing | Joe Dante | Director |
| Crew | Mike Johnson | Stunts |
| Costume & Make-Up | Rob Bottin | Makeup Effects Designer |
| Crew | Corey Michael Eubanks | Stunts |
| Crew | Al Wyatt Sr. | Stunts |
| Crew | Cindy Wills | Stunts |
| Crew | Simone Boisseree | Stunts |
| Crew | Dick Warlock | Stunts |
| Crew | Steven Lambert | Stunt Double |
| Sound | Rod Stewart | Songs |
| Visual Effects | Michael Wood | Special Effects Supervisor |
| Visual Effects | Dennis Muren | Visual Effects Supervisor |
| Camera | Andrew Laszlo | Director of Photography |
| Production | Mike Fenton | Casting |
| Production | Jane Feinberg | Casting |
| Production | Judy Taylor | Casting |
| Production | Chip Proser | Co-Producer |
| Editing | Kent Beyda | Editor |
| Art | James H. Spencer | Production Design |
| Production | Frank Marshall | Co-Executive Producer |
| Production | Kathleen Kennedy | Co-Executive Producer |
| Production | Jon Peters | Executive Producer |
| Production | Steven Spielberg | Executive Producer |
| Production | Peter Guber | Executive Producer |
| Writing | Chip Proser | Story |
| Production | Michael Finnell | Producer |
| Production | John C. Broderick | Unit Production Manager |
| Directing | Pat Kehoe | First Assistant Director |
| Directing | Carol Green | Second Assistant Director |
| Sound | Mark Mangini | Supervising Sound Editor |
| Art | William F. Matthews | Art Direction |
| Art | Richard C. Goddard | Set Decoration |
| Costume & Make-Up | Rosanna Norton | Costume Design |
| Directing | Anne Warner | Script Supervisor |
| Editing | Mark Goldblatt | Additional Editor |
| Sound | Kenneth Hall | Music Editor |
| Sound | Warren Hamilton Jr. | Sound Editor |
| Sound | James Matheny | Sound Editor |
| Sound | Teresa Eckton | Sound Editor |
| Sound | Wayne Allwine | Sound Editor |
| Sound | John Pospisil | Sound Editor |
| Sound | Ken King | Production Sound Mixer |
| Sound | Douglas Vaughan | Boom Operator |
| Sound | Robert J. Litt | Sound Re-Recording Mixer |
| Sound | Steve Maslow | Sound Re-Recording Mixer |
| Sound | Elliot Tyson | Sound Re-Recording Mixer |
| Lighting | James Plannette | Gaffer |
| Camera | Ray Kinzer | Key Grip |
| Crew | Glenn Randall Jr. | Stunt Coordinator |
| Art | Michael Muscarella | Construction Coordinator |
| Art | Craig Raiche | Property Master |
| Art | Judy Cammer | Set Designer |
| Art | Gene Nollman | Set Designer |
| Costume & Make-Up | Stephen Abrums | Makeup Artist |
| Costume & Make-Up | John Rizzo | Makeup Artist |
| Costume & Make-Up | Joy Zapata | Hairstylist |
| Costume & Make-Up | Barbara Lorenz | Hairstylist |
| Editing | Terry Hager | Color Timer |
| Art | Wayne Fitzgerald | Title Designer |
| Art | David Oliver Pfeil | Title Designer |
