FBI agent Neville Flynn boards a flight from Honolulu, Hawaii to Los Angeles, escorting a key witness to testify against a mob boss at an upcoming trial. An on-board assassin releases a crate full of hundreds of deadly venomous snakes in an attempt to eliminate the witness. Flynn and a host of frightened passengers and crew must band together to survive the slithery threat.
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| Directing | David R. Ellis | Director |
| Editing | Mindy Elliott | First Assistant Editor |
| Production | Erik Holmberg | Executive In Charge Of Production |
| Directing | Cindy Smith | Second Assistant Director |
| Production | Justis Greene | Unit Production Manager |
| Directing | Paula Janos | Additional Second Assistant Director |
| Costume & Make-Up | Allan A. Apone | Makeup Artist |
| Costume & Make-Up | Renee Dombrosky | First Assistant Hairstylist |
| Costume & Make-Up | Marianne Olsen | Makeup Artist |
| Directing | Adam Lawson | First Assistant Director (Prep) |
| Crew | Perry Baycroft | Carpenter |
| Costume & Make-Up | Megan Harkness | First Assistant Makeup Artist |
| Costume & Make-Up | Monica Huppert | Key Makeup Artist |
| Directing | Freddie Hice | Second Unit Director |
| Art | Wendy J. Findlay | Construction Buyer |
| Art | Mario Tomas-Niedworok | Paint Coordinator |
| Sound | Harry Cohen | Sound Designer |
| Art | Vivien Nishi | Set Designer |
| Sound | Tom Bellfort | Supervising Sound Editor |
| Production | Delia Circelli | Production Supervisor |
| Directing | Adrian Diepold | Third Assistant Director |
| Art | Timothy Burgard | Storyboard Artist |
| Crew | Jay Vinitsky | Post Production Supervisor |
| Art | Mark Francis | Assistant Property Master |
| Sound | Nerses Gezalyan | Foley Recordist |
| Art | Jan Reeves | Lead Painter |
| Art | Danelle Vierkant | Painter |
| Costume & Make-Up | Robert A. Pandini | Key Hair Stylist |
| Directing | Rudy Van Zyl | Second Second Assistant Director |
| Art | Michelle Gasque | Art Department Coordinator |
| Crew | Mark Fay | Cableman |
| Sound | Steve Mann | Sound Effects Editor |
| Art | R.D. 'Luther' Fairbairn | Property Master |
| Production | Jody Levin | Executive In Charge Of Post Production |
| Crew | Valerie Shmakin | Scenic Artist |
| Sound | Donald D. Brown | Boom Operator |
| Sound | John Cannon | Assistant Sound Editor |
| Art | Zoe Jirik | Set Decoration Buyer |
| Art | Jeremy Hanen | Set Dresser |
| Production | Randy Hutniak | Art Department Production Assistant |
| Costume & Make-Up | James Kilcher | On Set Dresser |
| Sound | Ian Ferguson | Sound Assistant |
| Sound | Michael McGee | Production Sound Mixer |
| Art | Bayard Baudoin | Painter |
| Art | Dave Emmonds | Head Greensman |
| Art | Sam Clemens | Standby Painter |
| Production | Caroline Belisle | Administration |
| Visual Effects | Thierry Delattre | Visual Effects Supervisor |
| Crew | Robert Alonzo | Utility Stunts |
| Production | Katherine Keizer | Extras Casting Coordinator |
| Costume & Make-Up | Shane Deschamps | Costume Set Supervisor |
| Crew | Jon Davidson | Production Controller |
| Sound | Greg Steele | ADR Mixer |
| Crew | Eric Bullock | Special Effects |
| Art | Doug White | Location Scout |
| Production | Andrea Larsen | First Assistant Accountant |
| Sound | Greg Zimmerman | ADR Recordist |
| Production | Olivier Beaulieu | Production Assistant |
| Camera | Kevin Black | Key Grip |
| Lighting | Jonathan Bosse | Rigging Grip |
| Camera | Ryan Copeland | Dolly Grip |
| Camera | Craig Haagensen | Director of Photography |
| Visual Effects | David J. McGraw | 24 Frame Playback |
| Camera | Richard McSeeney | Camera Trainee |
| Sound | Gabriel J. Serrano | Sound Recordist |
| Visual Effects | Alex Burdett | Special Effects Supervisor |
| Crew | Dan Akers | Compositor |
| Visual Effects | Miguel Arranz | Digital Compositor |
| Camera | Sandes Ashe | First Assistant Camera |
| Lighting | Rick Crum | Electrician |
| Costume & Make-Up | Lanny Campbell | Ager/Dyer |
| Costume & Make-Up | Askia Won-Ling Jacob | Costumer |
| Editing | Gary Burritt | Negative Cutter |
| Editing | Curtis Lindersmith | Digital Intermediate Editor |
| Production | Deborah D. Bose | Location Manager |
| Sound | Tom Calderaro | Orchestrator |
| Crew | Mark Brown | Transportation Captain |
| Production | Jill Anderson | Payroll Accountant |
| Production | Rick Coffee | Post Production Accountant |
| Sound | James Moriana | Foley Artist |
| Sound | Hugh Waddell | ADR Editor |
| Costume & Make-Up | Gideon Hay | Special Effects Makeup Artist |
| Camera | Tommy Lohmann | "A" Camera Operator |
| Editing | Kenneth Marsten | Assistant Editor |
| Production | Chaunce Drury | First Assistant Production Coordinator |
| Sound | Christopher Sidor | Sound Engineer |
| Sound | Mark Weingarten | Sound Mixer |
| Crew | Dennis Briest | Special Effects Assistant |
| Crew | Ed Anders | Stunt Double |
| Crew | Annie Ellis | Stunt Coordinator |
| Camera | Allison Beda | Second Assistant Camera |
| Production | Terry Edinger | Production Accountant |
| Crew | Justin Bertges | Special Effects Technician |
| Crew | Rick Lazzarini | Animatronics Supervisor |
| Production | Jeff Barnes | Production Executive |
| Crew | Peter Lloyd | Visual Effects Art Director |
| Production | James McKenzie Moore | Casting Assistant |
| Production | Lisa Ratke | Extras Casting |
| Costume & Make-Up | Alejandro M. Hernandez | Set Costumer |
| Editing | Alexander J. Harper | Editorial Production Assistant |
| Sound | Mark Adams | Musician |
| Sound | Michelle Pazer | Dialogue Editor |
| Visual Effects | Michael Cozens | Lead Animator |
| Camera | Cyrus Block | Camera Operator |
| Costume & Make-Up | Janice MacIsaac | Assistant Costume Designer |
| Crew | David Weston | Transportation Co-Captain |
| Crew | Paul Archer | Assistant Chef |
| Production | Jules Carideo | Production Coordinator |
| Production | Heike Brandstatter | Casting |
| Visual Effects | Marie-Claude Aubry | Visual Effects Coordinator |
| Visual Effects | Paul Griffin | Animation Supervisor |
| Camera | Hans Bjerno | Aerial Director of Photography |
| Crew | Ken Decker | Generator Operator |
| Crew | Kelly Denismore | Chef |
| Lighting | Kirk Bartolata | Best Boy Electric |
| Camera | Sean P. Fickert | Best Boy Grip |
| Crew | Scott Steyns | Playback Coordinator |
| Camera | Terry Wolcott | Camera Loader |
| Visual Effects | Ed Mendez | Compositing Supervisor |
| Camera | Yvonne Chu | Assistant Camera |
| Lighting | Michael Mayo | Rigging Gaffer |
| Lighting | Robert J. Reilly | Key Rigging Grip |
| Crew | Felix Fanzega | Driver |
| Crew | Ari Ben Ron | Craft Service |
| Visual Effects | Steve Dellerson | Visual Effects |
| Visual Effects | Lindsay M. Hoppe | Rotoscoping Artist |
| Costume & Make-Up | Clare McLaren | Truck Costumer |
| Production | Spencer Hon Lui | Second Assistant Production Coordinator |
| Visual Effects | Romain Bayle | Matte Painter |
| Crew | Jeff Goldman | Digital Effects Supervisor |
| Crew | David Legault | Visual Effects Editor |
| Lighting | Bill Dawson | Gaffer |
| Production | Terri Douglas | ADR Voice Casting |
| Production | Kara Lipson | Casting Associate |
| Production | Rachel Faith Hanson | Post Production Coordinator |
| Editing | Steve Lemley | Color Timer |
| Crew | William Ballard | Transportation Coordinator |
| Crew | Malcolm Dane | Stand In |
| Crew | Tom Felcan | Armorer |
| Crew | Brian Poor | Animatronics Designer |
| Crew | Danny Torres | Systems Administrators & Support |
| Crew | Lesley Aletter | Stunts |
| Production | Kent Matsuoka | Assistant Location Manager |
| Sound | Dana Sano | Music Consultant |
| Crew | Lap Van Luu | Systems Administrators & Support |
| Visual Effects | Janet Muswell | Visual Effects Producer |
| Crew | David Joshi | Video Assist Operator |
| Crew | Robert Milicevic | Security |
| Art | Nina Saxon | Title Designer |
| Crew | Marissa Schwierjohn | Animal Wrangler |
| Crew | Paul Prokop | Executive in Charge of Finance |
| Production | Shauna Sanders | Assistant Production Coordinator |
| Production | Lee Anne Muldoon | Publicist |
| Production | Gary Levinsohn | Producer |
| Art | Erin Boyd | Set Decoration |
| Production | Tawny Ellis | Associate Producer |
| Production | Craig Berenson | Producer |
| Production | Jeff Katz | Associate Producer |
| Production | Heather Meehan | Associate Producer |
| Production | Justis Greene | Executive Producer |
| Production | Toby Emmerich | Executive Producer |
| Production | Penney Finkelman Cox | Executive Producer |
| Production | Don Granger | Producer |
| Production | George Waud | Executive Producer |
| Production | Stokely Chaffin | Executive Producer |
| Crew | Cheyenne Ellis | Stunts |
| Crew | Andrea Kinsky | Stunt Double |
| Crew | Krista Bell | Stunts |
| Crew | Clay Cullen | Stunt Double |
| Crew | Ashlea Earl | Stunts |
| Crew | Rikki Gagne | Stunts |
| Crew | Laura Lee Connery | Stunts |
| Crew | Lauro David Chartrand-DelValle | Stunts |
| Production | Sandra Rabins | Executive Producer |
| Crew | Doug Chapman | Stunts |
| Crew | Casey O'Neill | Stunts |
| Editing | Howard E. Smith | Editor |
| Sound | Robb Boyd | Music Editor |
| Writing | John Heffernan | Screenplay |
| Art | Jaymes Hinkle | Production Design |
| Costume & Make-Up | Karen L. Matthews | Costume Design |
| Art | Mary-Lou Storey | Set Decoration |
| Writing | Sebastian Gutierrez | Screenplay |
| Camera | Adam Greenberg | Director of Photography |
| Camera | Tommy Lohmann | Camera Operator |
| Sound | Trevor Rabin | Original Music Composer |
| Camera | Tommy Lohmann | Steadicam Operator |
| Camera | James Dittiger | Still Photographer |
| Directing | Kelly Moon | Script Supervisor |
| Art | John Alvarez | Art Direction |
| Production | Mindy Marin | Casting |
| Writing | John Heffernan | Story |
| Writing | David Dalessandro | Story |
| Art | Jan Kobylka | Construction Coordinator |
| Crew | Kylie Furneaux | Stunt Double |
| Art | Joe Colwell | Sculptor |
| Crew | Freddie Hice | Stunt Coordinator |
| Directing | John MacCarthy | Second Unit First Assistant Director |
| Crew | Crystal Dalman | Stunts |
| Crew | Gerald Paetz | Stunt Driver |
