Buffalo Bill and Wild Bill Hickok join forces to establish a mail route that can get mail from St. Joseph, Missouri, to Sacramento, California, in ten days. Along the way they must battle bad weather, hostile Indians and outlaws intent on robbing the mail and shutting down the entire operation.
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| Directing | Jerry Hopper | Director |
| Art | Albert Nozaki | Art Direction |
| Art | Sam Comer | Set Decoration |
| Costume & Make-Up | Edith Head | Costume Design |
| Production | Nat Holt | Producer |
| Writing | Charles Marquis Warren | Screenplay |
| Art | Hal Pereira | Art Direction |
| Writing | Frank Gruber | Story |
| Art | Bertram C. Granger | Set Decoration |
| Editing | Eda Warren | Editor |
| Camera | Ray Rennahan | Director of Photography |
| Sound | Paul Sawtell | Original Music Composer |
