Mutant snakes survived a terrorist attack on a government laboratory, and they now threaten the town of Santa Mira Springs, California. Seismic activity has brought snakes to the surface, where residents are being bitten. Victims can transmit the virus to healthy persons. The military puts the town under quarantine. Local physicians try to control the epidemic, while the military is primarily concerned with keeping the virus a secret.
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| Writing | Sean McGinly | Writer |
| Writing | Dan Golden | Writer |
| Directing | Fred Olen Ray | Director |
| Sound | Neal Acree | Music |
| Production | Alan B. Bursteen | Executive Producer |
| Production | Alison Semenza | Producer |
| Art | Steve Ralph | Production Design |
| Production | Jim Wynorski | Producer |
| Editing | Randy Carter | Editor |
| Costume & Make-Up | Robert Constant | Costume Design |
| Camera | Andrea V. Rossotto | Director of Photography |
| Art | Linda Louise Sheets | Art Direction |
| Costume & Make-Up | Stefanie Owens | Makeup Department Head |
| Crew | Ellen Statham | Stunts |
| Crew | Bob Bragg | Stunt Coordinator |
| Crew | Patrick J. Statham | Stunts |
| Crew | Robert Powell | Stunts |
| Crew | Paul E. Short | Stunts |
| Crew | Steve Hart | Stunts |
| Camera | Gary Graver | Additional Photography |
| Camera | Mac Ahlberg | Second Unit Director of Photography |
| Crew | Matthew R. Anderson | Stunts |
| Camera | Donald G. Jackson | Additional Photography |
