The story is the bridges the gap of Assassin's Creed II and Assassin's Creed Brotherhood. After the destruction of Monteriggioni in the year 1500, Ezio met with Leonardo Da Vinci to gather information about the Pope's son, Cesare Borgia. Leonardo tells Ezio of Cesare's rise to power.
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| Writing | Jean Guesdon | Story |
| Writing | Ethan Petty | Screenplay |
| Production | Serge Hascoet | Executive Producer |
| Production | Jean-Jacques Tremblay | Executive Producer |
| Sound | Jesper Kyd | Music |
| Writing | Ethan Petty | Story |
| Art | Nicolas Drolet | Art Direction |
| Writing | Louis-Pierre Pharmand | Story |
| Writing | Jeffrey Yohalem | Story |
| Production | Yves Guillemot | Executive Producer |
| Production | Yannis Mallat | Executive Producer |
| Production | Sebastien Puel | Executive Producer |
| Sound | Inon Zur | Music |
| Production | Louis-Pierre Pharmand | Producer |
| Directing | Laurent Bernier | Director |
