The Substance

The Substance (2024)

If you follow the instructions, what could go wrong?

  • Genre: Horror, Science Fiction
  • Release Date: 2024-09-07
  • User Rating: 7.2/10 from 2662 ratings
  • Runtime: 2h 21min
  • Language: English
  • Production Company: Working Title Films
  • Production Country: France, United Kingdom
  • Director: Coralie Fargeat
star 7.2/10
From 2,662 Ratings
7.4

Summary

A fading celebrity decides to use a black market drug, a cell-replicating substance that temporarily creates a younger, better version of herself.

The Substance Trailer

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  • Demi Moore

    as Elisabeth
  • Margaret Qualley

    as Sue
  • Dennis Quaid

    as Harvey
  • Edward Hamilton-Clark

    as Fred
  • Gore Abrams

    as Oliver
  • Oscar Lesage

    as Troy
  • Christian Erickson

    as Man at Diner
  • Robin Greer

    as Male Nurse
  • Tom Morton

    as Doctor
  • Hugo Diego Garcia

    as Diego - Boyfriend
  • Daniel Knight

    as Casting Director
  • Jonathon Carley

    as Assistant Casting Director
  • Jiselle Henderkott

    as Girl Auditioning / New Year's Eve Show Dancer
  • Akil Wingate

    as TV Host
  • Vincent Colombe

    as Man in Suit #1 - Harvey's Office
  • Billy Bentley

    as Man in Suit #2
  • Lennard Ridsdale

    as Man in Suit #3
  • Jordan Ford Silver

    as Assistant Director - Pump It Up Show
  • Oscar Salem

    as 2nd Assistant Director - Pump It Up Show
  • Viviane Bossina

    as Sue's Assistant
  • Matthew Luret

    as Floor Runner
  • Jana Bittnerová

    as Maria
  • Olivier Raynal

    as Alan - 2nd Agent
  • Tiffany Hofstetter

    as Stylist
  • Nicolas Royer

    as Guy in the Elevator
  • Nathan Rippy

    as Assistant Director - New Year's Eve Show
  • Manon Arizmendi

    as Little Girl - New Year's Eve Show
  • Virginie Kotlinski

    as Mother - New Year's Eve Show
  • Brett Gillen

    as Director of Photography - New Year's Eve Show
  • Charlotte Marquardt

    as Screaming Woman
  • Léa Hengl

    as Screaming Woman
  • Gaëlle Raymond

    as Screaming Woman
  • Claire Lemaire

    as Screaming Woman
  • Lila Boughoufala

    as Screaming Woman
  • Aurélien Lorgnier

    as Screaming Man
  • Ivan Sellier

    as Screaming Man
  • Philip Schurer

    as Screaming Man
  • Christian Bourmier

    as Shareholder
  • Martin Graham

    as Shareholder
  • Christian Bordeleau

    as Shareholder
  • Patrick Hamel

    as Shareholder
  • Didier Dhondt

    as Shareholder
  • Jacques-Yves Dorges

    as Shareholder
  • Jean-Claude Matthey

    as Shareholder
  • Olivier Jarcin

    as Shareholder
  • Jean-Luc Magneron

    as Shareholder
  • Charlotte Murray

    as Allison - Diner Waitress
  • Aaron Kahn

    as Greeting Person
  • Gabriela Arnon

    as Greeting Person
  • Nancy Josephson Lahoussine

    as Greeting Person
  • Andrew Eldridge

    as Greeting Person
  • Denise Powers

    as Greeting Person
  • Bryan Jones

    as Greeting Person
  • Adam Carage

    as Happy Birthday Person
  • Maria McClurg

    as Happy Birthday Person
  • Andrew Desmond

    as Happy Birthday Person
  • Rebecca Lafont

    as Happy Birthday Person
  • Laura Puech

    as Isabella
  • Ryan Chidester

    as Stagehand
  • Céline Vogt

    as Elisabeth (Young) - Walk of Fame
  • Yannick Guérin

    as Clumsy Burger Guy - Walk of Fame
  • Jean Miel

    as Worker Walk of Fame
  • Paul Descoings

    as Worker Walk of Fame
  • Benoit Lévêque

    as Worker Walk of Fame
  • Arthur Molinet

    as Cocktail Bartender
  • Manon Sachot

    as Cocktail Lounge Couple
  • Bastien Jorelle

    as Cocktail Lounge Couple
  • Kelly Hoarau

    as Female Assistant - Towel
  • Michel Juskiewicz

    as George - Harvey's Friend
  • Louise Greggory

    as Restaurant Waitress
  • Christophe Sartirano

    as Guy Looking at Sue
  • Florent Torres

    as Guy Looking at Sue
  • Romain Caldeira

    as Billboard Technician
  • Barthelemy Thomas

    as Billboard Technician
  • Axel Baille

    as Photographer
  • Ashley Lambert

    as Additional Voices (voice)
  • Ranjani Brow

    as Additional Voices (voice)
  • Chase Fein

    as Additional Voices (voice)
  • Shane Sweet

    as Additional Voices (voice)
  • William Calvert

    as Additional Voices (voice)
  • Michael Corbett

    as Additional Voices (voice)
  • Stephen Apostolina

    as Additional Voices (voice)
  • Yann Bean

    as The Substance (voice)
  • Audjyan Alcide

    as Pump It Up Show Dancer
  • Jonathan Jenvrin

    as Pump It Up Show Dancer
  • Mimi Maury

    as Pump It Up Show Dancer
  • Amelye Solange

    as Pump It Up Show Dancer
  • Kévin Table

    as Pump It Up Show Dancer
  • Laura Boera

    as Sparkle Your Life Show Dancer
  • Cissy Duc

    as Sparkle Your Life Show Dancer
  • Sophie Mercier

    as Sparkle Your Life Show Dancer
  • Marie Valton

    as Sparkle Your Life Show Dancer
  • Katrina Budzynski

    as New Year's Eve Show Dancer
  • Alicia Maury

    as New Year's Eve Show Dancer
  • Megane Adamik

    as New Year's Eve Show Dancer
  • Annalisa Pagnotta

    as New Year's Eve Show Dancer
  • Maelle Dantigny

    as New Year's Eve Show Dancer
  • Aleksandra Fontaine Kedzierska

    as New Year's Eve Show Dancer
  • Pauline Sagetat

    as New Year's Eve Show Dancer
  • Agustina Fitzsimons

    as New Year's Eve Show Dancer
  • Elena Shcheglova

    as New Year's Eve Show Dancer
  • Eve Marchant

    as New Year's Eve Show Dancer
  • Lola Donati

    as New Year's Eve Show Dancer
  • Kate Matthews

    as New Year's Eve Show Dancer
  • Ophélie Jonard

    as New Year's Eve Show Dancer
  • Pauline Richard

    as New Year's Eve Show Dancer
  • Laureen Cappelliez

    as New Year's Eve Show Dancer
  • Daria Panchenko

    as New Year's Eve Show Dancer
  • Delphine Beaulieu

    as New Year's Eve Show Dancer
  • Victoria Brun

    as New Year's Eve Show Dancer
  • Cara Chapman

    as New Year's Eve Show Dancer
  • Katharine Matthews

    as New Year's Eve Show Dancer
  • Alexandra Faget

    as New Year's Eve Show Dancer
  • Clémence Juville

    as New Year's Eve Show Dancer
  • Margot L'Entete

    as New Year's Eve Show Dancer
  • Hillary Sukhonos

    as New Year's Eve Show Dancer
  • Matthew Géczy

    as Bob Haswell (uncredited)
  • Namory Bakayoko

    as Silhouette (uncredited)
  • Gregory Defleur

    as Happy Birthday Person (uncredited)
  • Coralie Fargeat

    as (uncredited)
Directing Anne Juin Third Assistant Director
Directing Matthieu de la Mortière First Assistant Director
Production Erik Baiers Executive Producer
Art Stanislas Reydellet Production Design
Crew Jérôme Gaspard Stunt Coordinator
Art Sebastian Lochmann Concept Artist
Costume & Make-Up Richard Martin Prosthetics Sculptor
Costume & Make-Up Frédérique Arguello Hair Department Head
Camera Benjamin Kračun Director of Photography
Crew Marie Bouvet Stunt Double
Costume & Make-Up Frédéric Balmer Special Effects Makeup Artist
Costume & Make-Up Andrea Leanza Prosthetics Sculptor
Art Krystell Morantin Assistant Art Director
Costume & Make-Up Denise Boccacci Prosthetic Makeup Artist
Visual Effects Bryan Jones Visual Effects Supervisor
Editing Jérôme Eltabet Editor
Art Cécilia Blom Set Decoration
Crew Joffrey Darel Stunt Driver
Crew Céline Richard Stunts
Camera Catherine Georges Camera Operator
Costume & Make-Up Camille Damag Costume Supervisor
Costume & Make-Up Fabienne Menguy Costume Supervisor
Art Baptiste Bonin Props
Crew Guillemette Buffet Stunt Double
Crew Stephane Girondeaud Stunts
Camera Steve de Rocco Camera Operator
Crew Arthur Delapierre Stunts
Crew Marie Sergeant Stunts
Crew Ahmed Chouikhi Stunts
Camera Chloè Acher Second Assistant Camera
Crew Yann Festinger Video Assist Operator
Production Noémie Lance Location Manager
Camera Eddy Trouillot Grip
Camera Laure Caniaux First Assistant Camera
Lighting Nahi Margot Electrician
Lighting Olivier Maurin Electrician
Art Nadege Marti Location Scout
Art Benjamin Bouygues-Faugeron Property Buyer
Camera Benjamin Colleye Additional First Assistant Camera
Camera Tanguy Goasguen Additional Grip
Camera Gustin Guillaume First Assistant Camera
Production Baptiste Herment Production Accountant
Lighting Olivier Sargatal Best Boy Electric
Crew Lucile Perez Stunts
Camera Vianne Burquier Camera Intern
Camera Marie-Sophie Daniel First Assistant Camera
Camera Jonas Poignant Third Assistant Camera
Lighting Guillaume Lemerle Gaffer
Camera Baptiste Marnière Digital Imaging Technician
Lighting Edouard Alvernhe Electrician
Camera Stella Libert First Assistant Camera
Editing Fabien Pascal Colorist
Editing Benjamin Durfort Assistant Editor
Crew Jérémie Delaboudinière Stunts
Camera Thomas Gros Key Grip
Camera William Renaud Grip
Production Katia Sourzac Location Production Assistant
Lighting Charles Droudun Electrician
Camera Ludovic Tobaldi Steadicam Operator
Camera Christine Tamalet Still Photographer
Directing Coralie Fargeat Director
Production Coralie Fargeat Producer
Production Tim Bevan Producer
Production Eric Fellner Producer
Production Alexandra Loewy Executive Producer
Production Nicolas Royer Executive Producer
Sound Raffertie Original Music Composer
Costume & Make-Up Marison De Special Effects Makeup Artist
Costume & Make-Up Olivier Afonso Special Effects Makeup Artist
Costume & Make-Up Jean-Marc Benois Key Hair Stylist
Costume & Make-Up Sandrine Denis Special Effects Makeup Artist
Costume & Make-Up Oriane Cattiaux Makeup Artist
Production Benjamin Celliez Unit Production Manager
Production Julia Besnier Production Accountant
Directing Clément Audebrand Third Assistant Director
Production Pierre-Yves Frohard Production Coordinator
Crew Abraham Goldblat Post Production Supervisor
Art Barthelemy Thomas Set Dresser
Costume & Make-Up Caroline Vlieghe Hairstylist
Costume & Make-Up Dave Elsey Prosthetic Supervisor
Costume & Make-Up Lou Elsey Prosthetic Supervisor
Crew Louis Celnik Carpenter
Costume & Make-Up Marilyne Scarselli Hair Supervisor
Directing Benoit Seiller Second Assistant Director
Art Marion Didier Assistant Art Director
Costume & Make-Up Cynthia Scigliuto Makeup Artist
Production Honorine Sutter Assistant Production Manager
Art Elise Duvignau Props
Costume & Make-Up Stéphanie Guillon Key Makeup Artist
Costume & Make-Up Bryony Rumble Special Effects Makeup Artist
Directing Mateo Cejoco Third Assistant Director
Costume & Make-Up Mélissa Jacob Additional Hairstylist
Costume & Make-Up Lucky Nguyen Makeup Artist
Editing Coralie Fargeat Editor
Crew Tiva Nagchin Post Production Supervisor
Directing Louis Tellier Third Assistant Director
Costume & Make-Up Brian Kinney Special Effects Makeup Artist
Art Amélie Meseguer Assistant Set Decoration
Visual Effects Jean Miel Special Effects Supervisor
Directing Marianne Huet Script Supervisor
Visual Effects Guillaume Le Gouez Visual Effects Supervisor
Camera Guillaume Billy Camera Trainee
Production Raphaëlle Beck Extras Casting
Costume & Make-Up Elsa Manunta Set Costumer
Sound Guillaume Baurez Music Supervisor
Art Chloé Zobel Property Master
Visual Effects Jacob Rogers Digital Compositor
Production Jacques-Emmanuel Astor Extras Casting
Editing Jimmy Zhao First Assistant Editor
Art Marjane Texier Graphic Designer
Art Elsa Rolland Assistant Property Master
Camera Christophe Arnaud Additional Second Assistant Camera
Production Steve Sebir Assistant Location Manager
Visual Effects Louis Auger Digital Compositor
Camera Thomas Burgess Steadicam Operator
Crew Olaf Taittinger Special Effects
Visual Effects Téo L'Huillier Digital Compositor
Visual Effects Louis Lion Digital Compositor
Production Christophe Riso Assistant Location Manager
Production Isalys Gillet Location Assistant
Production Aurélie Boutet Casting Assistant
Costume & Make-Up Pierre Olivier Persin Prosthetics
Costume & Make-Up Pierre Olivier Persin Makeup Effects Designer
Art Stéphane Bécimol Art Direction
Art Marion De Villechabrolle Set Decoration
Editing Valentin Féron Editor
Costume & Make-Up Emmanuelle Youchnovski Costume Designer
Sound Valérie Deloof Sound Designer
Sound Patrick Christensen ADR Mixer
Sound Olga Pasternak Supervising Dialogue Editor
Sound Thomas Pichon Dialogue Editor
Sound Anna Devillaire ADR Editor
Sound Margaux Peyre Boom Operator
Sound Grégory Vincent Foley Artist
Sound Stéphane Thiébaut Sound Re-Recording Mixer
Sound Victor Fleurant Sound Editor
Sound Judah Getz ADR Mixer
Sound Antoine Swertvaegher Foley Editor
Sound Victor Praud Sound Re-Recording Mixer
Sound Emmanuelle Villard Sound Mixer
Sound Valérie Deloof Sound Editor
Sound Claire Bernengo Boom Operator
Sound Lucien Richardson Supervising Dialogue Editor
Production Laure Cochener Casting
Writing Coralie Fargeat Writer
Art Amélie Meseguer Art Direction
Art Arnaud Denis Art Direction
Art Gladys Garot Art Direction
Art Julie Plumelle Art Direction
Art Nathalie Vaïsse Art Direction

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